MTOR Inhibitor

Search with Google Search with Bing

Information
Drug Name
MTOR Inhibitor
Description
Entry(CIViC)
2
CIViC
Disease Mutation EL ET ED CS VO TR Pubmed Links
cancer FBXW7 MUTATION FBXW7 MUTATION B Predictive Supports Sensitivity/Response Somatic 2 24586741 Detail
breast cancer PTEN p.Arg233Ter (p.R233*)
( ENST00000371953.8, ENST00000472832.3, ENST00000688308.1, ENST00000700021.1, ENST00000700029.2, ENST00000713839.1 ) PTEN p.Arg233Ter (p.R233*)
( ENST00000371953.8, ENST00000472832.3, ENST00000688308.1, ENST00000700021.1, ENST00000700029.2, ENST00000713839.1 ) 		D Predictive Supports Sensitivity/Response Somatic 4 20085938 Detail
Annotation
Description Associated Genes Associated Variants Sensitivity Supported Source Links
418 patients with advanced cancer were screened fo... FBXW7 FBXW7 MUTATION FBXW7 MUTATION Sensitivity true CIViC Evidence detail
Cells with PTEN deficiency have been shown to exhi... PTEN PTEN p.Arg233Ter (p.R233*)
( ENST00000371953.8, ENST00000472832.3, ENST00000688308.1, ENST00000700021.1, ENST00000700029.2, ENST00000713839.1 ) PTEN p.Arg233Ter (p.R233*)
( ENST00000371953.8, ENST00000472832.3, ENST00000688308.1, ENST00000700021.1, ENST00000700029.2, ENST00000713839.1 ) 		Sensitivity true CIViC Evidence detail